Joslin Diabetes Center

  • Research Assistant (Pathophysiology & Molecular Pharmacology)

    Location US-MA-Boston
    Posted Date 1 month ago(9/19/2018 9:45 AM)
    Job ID
    # Positions
    Research - Research
  • Overview

    Joslin Diabetes Center, the world’s leading specialist in the management of and research for a cure of diabetes, has a new and exciting entry-level opportunity in its Pathophysiology & Molecular Pharmacology lab!


    We are looking for an energetic, strong research assistant to work with animal models of insulin resistance and diabetes.  The research assistant will assist with analyses of glucose homeostasis and the development of insulin resistance in transgenic and knock-out mice. (requires direct contact with the mice, including injections of glucose and drugs and obtaining blood samples for measurements of glucose, insulin and other substances and genotyping and phenotyping of the mice.)


    This is an exciting opportunity for an entry-level or recent graduate to work with our diverse, experienced team and build expertise in the sought-after field of Pathophysiology & Molecular Pharmacology research.



    • The successful applicant must be able to design experiments with appropriate controls and to interpret the derived data.
    • Genotype transgenic and knock-out mice using PCR
    • Perform GTT, ITT and hyperinsulinemic-euglycemic clamps for the metabolic characterization of animals.
    • Maintenance of mouse colony, including breeding, weighing, and monitoring food intake and response to medication.
    • Lab support (ordering supplies, coordinating glassware washing, repairs, buffer preparation)
    • Accurate record-keeping and data storage
    • Assist PI and lab members in organizing and maintaining plasmids, antibodies, cell lines, etc.
    • Organize clinical samples coming in from different sites; use the computer program Freezerworks to bar code the samples. Retrieve the samples from the freezers and organize for use.



    • The ideal candidate will have a bachelor’s degree in biochemistry, biology, molecular biology or related field.  
    • A Strong background in mammalian physiology, biochemistry and molecular/cellular biology is a plus. 
    • Previous experience with animals is highly preferred. 

    If this role seems like something that would be of interest to you, then we encourage you to apply!



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